Cryomicroscopy Research Scientist

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Amar Annamalai
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Cryomicroscopy Research Scientist

Cryomicroscopy Research Scientist

The Francis Crick Institute


£38,000 + per annum

Full Time

Contract Type:
Contract / Temporary

Placed on:
4th February 2015

13th March 2015

Job Ref:

The Francis Crick institute (the Crick) is a partnership between the Medical Research Council (MRC), Cancer Research UK (CRUK), the Wellcome Trust, University College London (UCL), Imperial College London and Kings College London. It is a registered charity whose purpose is to conduct biomedical research into all aspects of human health and disease.

The Institute will be a world-leading centre of biomedical research and innovation. It will promote connections between researchers and disciplines and between academic institutions, healthcare organisations and businesses. Dedicated to research excellence, the institute will have the scale, vision and expertise to tackle the most challenging scientific questions underpinning health and disease. It will be world-class with a strong national role—training scientists and developing ideas for public good. Due to open in November 2015, The Crick will be located in a new, purpose built research centre in central London (Brill Place next to St. Pancras International) and will house some 1,250 researchers and 250 support staff.

The position of Cryomicroscopy Research Scientist has been created to:

  • Perform work on experimental single particle cryomicroscopy of macromolecular complexes and/or tomography in the Rosenthal Group with a focus on instrumentation, data acquisition, and automation.
  • You will contribute to the management of instruments and development of new methods.


Specific objectives will include, but not be limited to:

  • Conducting a range of research activities and projects in the Rosenthal laboratory including the design and implementation of experimental protocols in electron cryomicroscopy, and work on methods for automatic data collection and image capture in the context of single particle projects and tomography.
  • Contributing to the management of high-end cryomicroscopes closely related to the group’s research activities including the FEI Polara and Spirit microscopes, detectors, and associated equipment, and maintaining and updating microscope-related computer hardware and software.
  • Communicating at group discussions all aspects of laboratory and scientific project management, contributing to the preparation of scientific manuscripts, internal reports, and activities related to the group’s transfer to the Francis Crick Institute.

Person Specification:
The post holder should embody and demonstrate our core Crick values: Bold, Imaginative, Open, Dynamic and Collegiate, in addition to the following:


  • A PhD in biological, physical, or engineering sciences.
  • Research experience and expertise in electron microscopy.
  • Ability to plan time efficiently, excellent communication skills, and ability to work both independently and in a team setting.


  • Experience in experimental electron cryomicroscopy, field emission gun microscopes, and/or electron detection.
  • Experience in data analysis single particle images or tomography data.
  • Postdoctoral experience in conducting cutting-edge research in experimental electron microscopy and/or structural biology.
  • Demonstration of scientific expertise and excellence through authorship in peer-reviewed publications in internationally recognized scientific journals.

If you are interested in applying for this role, please send your CV and covering letter, explaining your motivation and suitability for this role including details of your current salary, to Bharkavy Gajendra at, quoting ‘Research Scientist in Cryomicroscopy- Ref 204.’ in the subject line.

The closing date for applications is Friday 13th March at 5pm.

For any questions relating to this role, please contact Dr Peter Rosenthal via or Bharkavy Gajendra, Recruitment Administrator via eval(unescape('%64%6f%63%75%6d%65%6e%74%2e%77%72%69%74%65%28%27%3c%61%20%68%72%65%66%3d%22%6d%61%69%6c%74%6f%3a%62%67%61%6a%65%6e%64%40%6e%69%6d%72%2e%6d%72%63%2e%61%63%2e%75%6b%22%3e%62%67%61%6a%65%6e%64%40%6e%69%6d%72%2e%6d%72%63%2e%61%63%2e%75%6b%3c%2f%61%3e%27%29%3b')) .