Synthetic Organic Chemistry - Cancer Research UK Cancer Therapeutics Unit

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Synthetic Organic Chemistry - Cancer Research UK Cancer Therapeutics Unit

REF: B420
The Institute of Cancer Research (ICR) (a college of the University of London) is a world-class cancer research organisation with HEFCE RAE ratings of international excellence across all of its research programmes. In partnership with The Royal Marsden NHS Foundation Trust, we form the largest comprehensive cancer centre in Europe.

The Cancer Research UK Cancer Therapeutics Unit, a Section of the ICR, is a multidisciplinary 'bench to bedside' centre, comprising around 160 staff dedicated to the discovery and development of novel therapeutics for the treatment of cancer. At least 3 positions are available for postdoctoral chemists who will be located in well-equipped laboratories in Sutton. The Cancer Therapeutics Unit’s exciting goal is to discover high quality drug candidates for validated biological targets and to progress these candidates to clinical trial. All the scientific disciplines are in place to make this possible. Our chemists work alongside world-class biologists and drug metabolism specialists focusing on new molecular targets emerging from human genome and ground breaking cell biology research.

These are postdoctoral positions in synthetic organic chemistry applied to the discovery and optimisation of new drugs to treat cancer. The chemical starting points include hits from bioassays, virtual screening and structure-based design approaches. The successful candidates will apply their synthetic organic chemistry knowledge to the synthesis of molecules of interest as anticancer agents. In addition, the successful candidates will develop skills in medicinal chemistry, target design and selection, as well as broader drug discovery knowledge.

Knowledge, experience and achievement in synthetic chemistry are essential. Successful applicants will have ample opportunity to develop additional skills in post. This is an ideal opportunity for enthusiastic, committed chemists to make an important contribution to improved therapies for cancer patients, while gaining experience and training in drug discovery skills in an institute with a track record of success.
The posts will either be in our Medicinal Chemistry 4 Team (Leader: Dr Swen Hoelder) or our Gene and Oncogene Targeting Team (Leader: Professor Caroline Springer). Appointments will be on a two-year contract in the first instance and salary will be in the range of £29,256 to £34,993.

To apply please email your CV and covering letter (addressing where you meet the person specification and incl. the names and addresses of two referees), to: eval(unescape('%64%6f%63%75%6d%65%6e%74%2e%77%72%69%74%65%28%27%3c%61%20%68%72%65%66%3d%22%6d%61%69%6c%74%6f%3a%72%65%63%72%75%69%74%6d%65%6e%74%40%69%63%72%2e%61%63%2e%75%6b%22%3e%72%65%63%72%75%69%74%6d%65%6e%74%40%69%63%72%2e%61%63%2e%75%6b%3c%2f%61%3e%27%29%3b')), quoting job reference number B420. For a job description and person specification please visit Alternatively you may call our 24 hour recruitment line on 020 7153 5475 begin_of_the_skype_highlighting              020 7153 5475      end_of_the_skype_highlighting.

In a separate email, please send your completed equal opportunities monitoring form to the same email address quoting the job reference number above.

Closing date for applications: 23rd February 2011

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