Postdoctoral Scientist – Applied Computational Biology and Bioinformatics
- Reference number: PI/12/17
- Salary in the range of £28,500 – £38,000 (dependent upon qualifications and experience)
- Three year fixed-term contracts
The Paterson Institute for Cancer Research, an Institute of The University of Manchester, is a world leading centre for excellence in cancer research. The Institute is core funded by Cancer Research UK, the largest independent cancer research organisation in the world. Our aim is to gain greater understanding of the fundamental basis of cancer development and apply that knowledge to develop new diagnostic tests, improved predictors of outcome and new treatment strategies. Our advanced research programmes therefore span the spectrum of cancer research, from the molecular and cellular basis of cancer, through to drug discovery to translational and clinical research. The Institute has outstanding laboratory facilities and exceptional core services, including microarrays, confocal microscopy, bioinformatics, histology and mass-spectrometry. We are situated in Manchester, England, a vibrant and dynamic city surrounded by some of the most beautiful countryside in the UK. The national and international transport links to Manchester are excellent.
We are seeking a highly motivated postdoctoral scientist interested in non-coding RNAs and the role they play regulating gene expression in cancer.
The post, within the Cancer Research UK Applied Computational Biology and Bioinformatics Group, will focus on the analysis of DNA, RNA and quantitative proteomics datasets generated by our in-house deep sequencing and proteomics facilities. The group uses the fission yeast S. pombe as a model system with which to explore the fundamental mechanisms of RNA-directed regulation (e.g. Bitton et al (2011) Molecular Systems Biology. msb.2011.90), and is interested in the behaviour of analogous pathways in human tumours. These are being investigated using a mixture of cell-line and primary tumour samples, encompassing a variety of different cancer types.
The research group is highly interdisciplinary, and features a mixture of software engineers, bioinformaticians, computational biologists and bench scientists. The successful candidate will have excellent communication skills and will relish working in a collaborative team. Substantial programming experience and a proven track record analysing large, complex datasets is a prerequisite, as is a PhD in computational biology or a related discipline. Direct and substantial experience performing in-depth analyses of high throughput biological data would convey a significant advantage, however, exceptional applicants from a purely computational background will also be considered.
Informal enquiries should be directed to Dr Crispin Miller: eval(unescape('%64%6f%63%75%6d%65%6e%74%2e%77%72%69%74%65%28%27%3c%61%20%68%72%65%66%3d%22%6d%61%69%6c%74%6f%3a%63%6d%69%6c%6c%65%72%40%70%69%63%72%2e%6d%61%6e%2e%61%63%2e%75%6b%22%3e%63%6d%69%6c%6c%65%72%40%70%69%63%72%2e%6d%61%6e%2e%61%63%2e%75%6b%3c%2f%61%3e%27%29%3b'))
To apply for this position, please visit our website: www.paterson.man.ac.uk
For applicants who are unable to download the information from our website, please contact the HR Department on 0161 446 3221, email: eval(unescape('%64%6f%63%75%6d%65%6e%74%2e%77%72%69%74%65%28%27%3c%61%20%68%72%65%66%3d%22%6d%61%69%6c%74%6f%3a%6a%6f%62%73%40%70%69%63%72%2e%6d%61%6e%2e%61%63%2e%75%6b%22%3e%6a%6f%62%73%40%70%69%63%72%2e%6d%61%6e%2e%61%63%2e%75%6b%3c%2f%61%3e%27%29%3b')) to have the information sent by post.
Deadline:May 04, 2012