Job Ref: 469/19195/BC
This is a fixed term post for three years
Project: Basal bodies organise the assembly and maintenance of cilia and flagella in eukaryotic cells. Most cells in the human body form a cilium or flagellum, which are required for either cell signaling and/or moving cells through fluid. Dysfunction of basal bodies, cilia and flagella are linked to a number of human diseases collectively called ciliopathies. Cilia and flagella are highly conserved cellular structures that are also required for cell motility and play an important role in the pathogenesis of a number of tropical parasites affecting Humans, including Trypanosoma brucei which causes African sleeping sickness. This project will investigate the early assembly steps of basal body duplication. The successful candidate will use a range of three dimensional bioimaging tools including electron tomography and investigate the protein composition using a range of molecular biology tools.
You will have:
a degree in a biological topic
a PhD in a biological topic
significant research experience in cell biology
a strong background in electron microscopy and imaging software and research experience in biological imaging and electron microscopy
an ability and willingness to carry out collaborative research.
For further details, please contact Dr Sue Vaughan at eval(unescape('%64%6f%63%75%6d%65%6e%74%2e%77%72%69%74%65%28%27%3c%61%20%68%72%65%66%3d%22%6d%61%69%6c%74%6f%3a%73%76%61%75%67%68%61%6e%40%62%72%6f%6f%6b%65%73%2e%61%63%2e%75%6b%22%3e%73%76%61%75%67%68%61%6e%40%62%72%6f%6f%6b%65%73%2e%61%63%2e%75%6b%3c%2f%61%3e%27%29%3b'))
Due to funding restrictions international applicants from outside the EU will need to demonstrate their eligibility to work in the UK.