Molecule of the Year 2009 is the Sleeping Beauty Transposase SB 100X

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Isidro A. T. Savillo
Isidro A. T. Savillo's picture
Molecule of the Year 2009 is the Sleeping Beauty Transposase SB 100X

  The ISMCBBPR (International Society for Molecular and Cell Biology and Biotechnology Protocols and Researches) has just announced that the Molecule of the Year 2009 is the Sleeping Beauty Transposase SB 100X. 

  Here is the publication of this winning molecule where the  Voters based their choice (plus the reviews, etc.) as the Molecule of the Year 2009:

Molecular evolution of a novel hyperactive Sleeping Beauty transposase enables robust stable gene transfer in vertebrates
Lajos Ma´te´s 1,6, Marinee K L Chuah 2,6, Eyayu Belay 2, Boris Jerchow1, Namitha Manoj1, Abel Acosta-Sanchez2, Dawid P Grzela 1, Andrea Schmitt 1, Katja Becker 1, Janka Matrai 2, Ling Ma 2, Ermira Samara-Kuko 2,Conny Gysemans3, Diana Pryputniewicz1, Csaba Miskey1, Bradley Fletcher4, Thierry VandenDriessche2,Zolta´n Ivics1& Zsuzsanna Izsva´k 1,5
1Max Delbruck Center for Molecular Medicine, Berlin, Germany. 2Flanders Institute for Biotechnology (VIB), Vesalius Research Center, University of Leuven, Leuven,Belgium. 3Department of Experimental Medicine, Laboratory for Experimental Transplantation, University of Leuven, Belgium. 4Department of Pharmacology and Therapeutics, University of Florida, College of Medicine, Gainesville, Florida, USA. 5Institute of Biochemistry, Biological Research Center of the Hungarian Academy of Sciences, Szeged, Hungary. 6These authors contributed equally to this work. Correspondence should be addressed to Z.I. ( or T.V.(
Received 17 December 2008; accepted 2 February 2009; published online 3 May 2009; doi:10.1038/ng.343
This can be accessed at:;;

Details and additional information including a Press Release Statement will soon be posted in the Molof theYear  2009 web site of ISMCBBPR



Prof. Isidro T. Savillo
President , ISMCBBPR