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Skipping exon 23 in mdx mice ameliorates cellular pathologies

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jonmoulton
United States

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Status: Frog Laureate
Frog Laureate
Topic Started by jonmoulton
on 1/12/2009 11:32 AM   
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This is another step toward using Morpholino oligos as therapeutics for Duchenne muscular dystrophy.

Doran P, Wilton SD, Fletcher S, Ohlendieck K. Proteomic profiling of antisense-induced exon skipping reveals reversal of pathobiochemical abnormalities in dystrophic mdx diaphragm. Proteomics. 2009 Jan 8. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/19132684

Jon D. Moulton, Ph.D.
Gene Tools, LLC
www.gene-tools.com


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