Currently approved therapeutic monoclonal antibodies:Name TargetOrthoclone OKT3 CD-3ReoPro GPIIbIIIa (integrin alphaIIbbeta3)Rituxan CD-20Zenapax IL-2Remicade TNF-alphaHerceptin HER-2Synagis RSVSimulect CD25Mylotarg CD33Campath CD52Humira TNF-alphaZevalin CD-20Xolair IgEBexxar CD-20Raptiva CD11alpha (alphaL integrin)Avastin VEGFErbitux EGFRTysabri VLA4 (alpha-4 integrin)Any I missed?
There are also monoclonals approved for use as imaging agents, I don't know if you'll want those in your list?http://www.fda.gov/medbull/oct96/radioant.html
Good point...We tend to focus on the therapeutics, but diagnostics seem to be an important area of growth as well.
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