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Therapeutic Monoclonal Antibodies

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pw_18

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Currently approved therapeutic monoclonal antibodies:

Name Target
Orthoclone OKT3 CD-3
ReoPro GPIIbIIIa (integrin alphaIIbbeta3)
Rituxan CD-20
Zenapax IL-2
Remicade TNF-alpha
Herceptin HER-2
Synagis RSV
Simulect CD25
Mylotarg CD33
Campath CD52
Humira TNF-alpha
Zevalin CD-20
Xolair IgE
Bexxar CD-20
Raptiva CD11alpha (alphaL integrin)
Avastin VEGF
Erbitux EGFR
Tysabri VLA4 (alpha-4 integrin)

Any I missed?

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 Posted May 04, 2005, 12:37 PM
Richard Taylor

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There are also monoclonals approved for use as imaging agents, I don't know if you'll want those in your list?

http://www.fda.gov/medbull/oct96/radioant.html

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Richard Taylor | http://www.biomarketing.co.uk

Posted May 05, 2005, 3:50 AM
pw_18

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Good point...We tend to focus on the therapeutics, but diagnostics seem to be an important area of growth as well.

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Posted May 05, 2005, 10:40 AM
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