Joseph G Hoffman
Born 19 Aug 1909; died 9 Dec 1974

American physicist and biophysicist who brought atomic isotopes into the battle against cancer. During WW II, he developed a radio proximity fuse and later was a health-physics scientist with "Manhattan Project." Hoffman studied nine accident victims of radiation disease at Los Alamos in Aug 1945 and May 1946. This research revealed for the first time that atoms of living human tissue could be transformed into radioactive atoms. He recognized "a completely new approach to studying the metabolism of atoms in living tissue and a new way of probing the complicated system of gene cells that determine heredity," and such knowledge was indispensable to understanding the mysteries of cancer research in which he engaged for the rest of his life.