Scientist Solutions: Life Science Discussions
 Refer a Friend    Link To Us    Bookmark Us       

      
 » Home » Drug Discovery/Manufacturing » Post Ideas/Find a Collaborator/Funding Opportunities » Myriad's Alzheimer’s Drug Flurizan Fails Clinical Trial

Other Topics
11/4/2008 01:29 PM
Denosumab lead investigat ...
10/5/2008 02:39 AM
Follow-on Biologics
8/29/2008 02:47 AM
Standardize herbal extrac ...
8/29/2008 01:53 AM
It's a risky business
8/12/2008 06:07 PM
US Department of Labor cl ...
5/6/2008 04:37 AM
Gene Therapy Improves Sig ...
3/9/2008 05:41 AM
Drug Discovery and Develo ...
2/27/2008 08:01 PM
Stem cell outfits a winne ...
2/8/2008 09:35 PM
Alnylam makes progress wi ...
1/23/2008 12:13 AM
FierceBiotech and FierceB ...
1/17/2008 12:35 PM
NSIAID
5/25/2007 05:38 AM
Need a help
5/10/2007 05:45 AM
Need help to get info reg ...
12/12/2006 07:58 PM
Vascular Surgeon Seeking ...
8/25/2006 10:13 PM
SDS-PAGE electrophoresis
7/26/2006 11:11 PM
A brief article about New ...
1/19/2006 03:18 AM
Dendrimers/new drug desig ...
12/10/2005 05:53 AM
Is It True To Say
11/2/2005 07:05 PM
contamination control /cr ...
6/13/2005 08:50 AM
cleaning validation
5/5/2005 08:26 AM
API Bioburden
4/19/2005 10:06 AM
snedds(self neno emulsify ...
Subscribet to topic
Add Reply  Add New Topic  Add New Poll
bottom of page RSS Feed 

Topic Feed

 

Myriad's Alzheimer’s Drug Flurizan Fails Clinical Trial

 [View Printable]
kumar

Frog Laureate

See
Similar
Scientists



View Blogs


Group: Moderators
Posts: 75
Joined: Aug 25, 2006







 Go to homepage of kumar Send a personal messsage to kumar Reply with a quote from this post Go to the top of the page

Myriad said the drug, called Flurizan, did not improve thinking ability by a statistically significant amount compared to a placebo. Nor did it improve the ability of patients to carry out daily activities. The company, based in Salt Lake City, said it would discontinue development of the drug.

Last year, Neuochem announced that a Phase III clinical trial had not demonstrated a statistically significant difference in favor of its tramiprosate treatment for Alzheimer's Disease a Phase III clinical trial. Since then Myriad's Flurizan has been under doubts too.

http://seekingalpha.com/article/45698-expect-pressure-on-myriad-genetics-following-trial-news

On 17th June, Wyeth and Elan Corp. reported that a mid-stage study for a drug (bapineuzumab) to treat Alzheimer's disease did not meet its goal. However, the results were encouraging enough for a subpopulation of patients (Alzheimer's patients lacking the gene, known as the ApoE4 allele) that the companies have moved into the final-stage of testing.

Eli Lilly & Company, is in late-stage testing of a drug that works somewhat similarly to Flurizan, by inhibiting an enzyme called gamma secretase.

Let's see what is reported in the upcoming ICAD (International Conference on Alzheimer's Disease) conference (July 26-31).

.........................

Posted Jun 30, 2008, 11:51 AM
top of page Add Reply  Add New Topic  Add New Poll

Forum Jump