Dear All
I made bilaterally ovariectomized rats and let them to stay 3 months, i.e. osteoporosis originated and increased due to the lack of estrogen....
but I measure ALP in their plasma and I found it higher than control...
what does this mean?
I am sure of my surgery technique to remove ovaries completely....but I am so confused about this....
Is there anybody have an idea about this
I hope anyone can help me....

What kind of ALP test did you do there are couple each detects different activities.
But I think that maybe this article would intrest you and may answer your question:
http://www.ncbi.nlm.nih.gov/pubmed/6504933?ordinalpos=4&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

Guy

thanx alot for your care about replying me...
but really I cannot get the fulltext of this article as I think it will benefit me so much and I have no access for old papers in my faculty
I hope you can help me....
Best regards