There is the ever-present potential for the transmission of viral diseases from the`manufacturing processes for Moab therapeutics. What are the best methods to implement an streamlining viral validation?

roudi said:

There is the ever-present potential for the transmission of viral diseases from the`manufacturing processes for Moab therapeutics. What are the best methods to implement an streamlining viral validation?

A relateively new technology trend that is being marketed by Sartorius (www.sartorius.com) is membrane adsorption.The product is called "Sartobind Q"., and the operation principle consists of a single pass of process fluid through a cellulosic, microporous membrane with a 3-5 micron diameter pore size rating and containing quaternary ammonium ligands covalently bound to the membrane. These ligands emove contaminants and viruses.
A company called : Vivascience has a kit for adenovirus purification. Check www.vivascience.com