Voiculescu O, Bertocchini F, Wolpert L, Keller RE, Stern CD. The amniote primitive streak is defined by epithelial cell intercalation before gastrulation. Nature advance online publication 10 October 2007 | doi:10.1038/nature06211

http://www.nature.com/nature/journal/vaop/ncurrent/abs/nature06211.html

This paper uses electroporation of Morpholino oligos into chick embryos to knock down genes involved in formation of the primitive streak. See the supplementary online information for videos.

jon:

What a great publication for the Morpholino technology!

Good day Tony,

They are getting more difficult to find -- not because the rate of publication using Morpholinos is decreasing (instead it is on the rise). Rather as Morpholinos have become a more established technology, investigators no longer mention in their abstracts that they used Morpholinos. My days of finding 90%+ of Morpholino papers with PubMed searches are over. I can do full-text search in PubMed Central and in HighWire Press, but these search only a fraction of the journals. I caught the Nature paper cited above by looking at the abstract and following a hunch -- then the online supplemental information provided the proof.

After shifting to industry, the old academic habits are often useful ;)

Best regards to you Tony,

- Jon