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 Targets of miRNAs on mRNAs have been protected using Morpholino oligos [View Printable]
jonmoulton

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By binding a Morpholino oligo onto the miRNA target site of an mRNA, that mRNA can be protected from translation inhibition caused by the miRNA.

Choi WY, Giraldez AJ, Schier AF.
Target Protectors Reveal Dampening and Balancing of Nodal Agonist and Antagonist by miR-430.
Science. 2007 Aug 30; [Epub ahead of print]
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Jon D. Moulton, Ph.D. Gene Tools, LLC www.gene-tools.com

Posted Sep 05, 2007, 23:58 PM
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