Dear All,
Just wanted to share my intrest in a new technology in Electron Microscopy. Scanning Photoionization Microscopy (SPIM)
How SPIM Works, How SPIM is Made
By comparing SPIM images of nanostructured gold films to scans using atomic force microscopy, which profiles surface topology, the researchers confirmed the correlations and physical mapping accuracy of the new technique. They also determined that lines in SPIM images correspond to spikes in electron energy, or current, and that contrast depends on the depth of electrons escaping from the metal as well as variations in material thickness.

http://www.nanoscienceworks.org/Members/siebo/Chandrakasan-to-Lead-MIT-Microsystems-Lab
http://medgadget.com/archives/2006/10/scanning_photoi.html