http://www.pubmedcentral.gov/articlerender.fcgi?tool=pmcentrez&artid=156588

Combined histomorphometric and gene-expression profiling applied to toxicology
Andres Kriete et al.


abstract
We have developed a unique methodology for the combined analysis of histomorphometric and gene-expression profiles amenable to intensive data mining and multisample comparison for a comprehensive approach to toxicology. This hybrid technology, termed extensible morphometric relational gene-expression analysis (EMeRGE), is applied in a toxicological study of time-varied vehicle- and carbon-tetrachloride (CCl4)-treated rats, and demonstrates correlations between specific genes and tissue structures that can augment interpretation of biological observations and diagnosis.

Scot E. DOwd Ph.D. said:

http://www.pubmedcentral.gov/articlerender.fcgi?tool=pmcentrez&artid=156588 Combined histomorphometric and gene-expression profiling applied to toxicology Andres Kriete et al. abstract We have developed a unique methodology for the combined analysis of histomorphometric and gene-expression profiles amenable to intensive data mining and multisample comparison for a comprehensive approach to toxicology. This hybrid technology, termed extensible morphometric relational gene-expression analysis (EMeRGE), is applied in a toxicological study of time-varied vehicle- and carbon-tetrachloride (CCl4)-treated rats, and demonstrates correlations between specific genes and tissue structures that can augment interpretation of biological observations and diagnosis.

Dear Dr. DOwd,

Were you involved in this research project or the paper was just too interesting? I f you were involved in this project, could you please explain more about toxicogenomics?