Please find a link to a PDF file that describes the whole cell Patch-Clamp technique.
It gives CFTR (Cystic Fibrosis Trancemembrane Conductance Regulator) as an example. It has a good explanation of the basics of this method.
http://pen2.igc.gulbenkian.pt/cftr/vr/d/hug_whole_cell_patch_clamp_tool_cftr_function.pdf
Guy