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software for structure analysis? [View Printable]
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lbates
Group: Member Posts: 2 Joined: Dec 24, 2004
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Does anyone know of any software that will suggest a structure for a protein given its amino acid sequence? Thanks
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Posted Dec 27, 2004, 20:53 PM |
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Bettye
Group: Member Posts: 134 Joined: Dec 29, 2004
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| lbates said: | | Does anyone know of any software that will suggest a structure for a protein given its amino acid sequence? Thanks |
mgenthreader or PSIPred
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| Posted Jan 06, 2005, 21:37 PM |
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biplabbose
Group: Member Posts: 5 Joined: Jan 26, 2005
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| lbates said: | | Does anyone know of any software that will suggest a structure for a protein given its amino acid sequence? Thanks |
Hi I will preffer to remind you that till date there is no software which can accurately predict 3_D structure from amino acid sequence alone. One can use homology modeling if there is any homologous protein with known 3-D structure. If there is no homologous protein then you are really in trouble as all sort of modeling depends upon on some sort of homology even threading softwares too. For homology modeling you can try swissport homology modeling server. Its good. best of luck Biplab visit My Home Pagehttp://www.biplabbbose.wb.st
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......................... Biplab Bose
Assistant Professor,
Department of Biotechnology,
Indian Institute of Technology Guwahati;
Guwahati,
Assam, India, PIN- 781039
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| Posted Jan 27, 2005, 0:09 AM |
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vanishing
Group: Member Posts: 129 Joined: Apr 25, 2005
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A lot of people would be out of work, if a program existed that worked presisely. With RNA you can make precise structure predictions, no program exists that does so for proteins really well. But there are some prediction servers. I can give you what I have found on the Internet and send you my links.
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| Posted Apr 26, 2005, 0:25 AM |
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holeung
Group: Member Posts: 10 Joined: May 06, 2005
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As others have stated, this is not reliable except for homology models. However, there have been significant recent breakthroughs in the area of ab initio structure prediction. You can try Robetta:
http://robetta.bakerlab.org/
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| Posted May 06, 2005, 22:22 PM |
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Reetu sharma
Group: Member Posts: 1 Joined: Oct 06, 2005
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| lbates said: | | Does anyone know of any software that will suggest a structure for a protein given its amino acid sequence? Thanks |
i agree with the fact that until now, no such software r present which could fully provide the 3-D structure of protein. though, people r working to develop such software. u can try swissport homology server for homologous proteins .
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| Posted Oct 07, 2005, 12:38 PM |
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maybetina
Group: Member Posts: 1 Joined: Nov 22, 2005
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| Reetu sharma said: | | lbates said: | | Does anyone know of any software that will suggest a structure for a protein given its amino acid sequence? Thanks |
i agree with the fact that until now, no such software r present which could fully provide the 3-D structure of protein. though, people r working to develop such software. u can try swissport homology server for homologous proteins . |
swiss-model is good. If u wanna do it urself, find homological template, and use modeller to do it. But ur result might only has 30% reliability. Anyway, molecule modeling by software is still not reliable yet.
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| Posted Nov 23, 2005, 3:51 AM |
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