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 uv metod for valdecoxib [View Printable]
humaira

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sir/madam,

please help me regarding the solubility of valdecoxib in oils.
.........................

 Posted Aug 21, 2006, 2:56 AM
vanishing

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this might help:

http://cat.inist.fr/?aModele=afficheN&cpsidt=16225562
.........................

Posted Jan 22, 2007, 0:47 AM
vanishing

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Cited from:
Liu et al., 2004
J. Chem. Eng. Data 2004, 49, 1847

Valdecoxib is chemically designated as 4-(5-
methyl-3-phenyl-4-isoxazolyl)benzenesulfonamide and is a
diaryl substituted isoxazole (see Figure 1). It has poor
solubility in water, that is, 10 íg/mL at 298.15 K.

The structure looks pretty unpolar and there is good solubility in 100%EtOH (>10 mg/ml)
So I suppose solubility in oil is high.

But what is your question? Do you want actual numbers?

p.s.:
if you use GOOGLE (!) and enter "solubility" and "valdecoxib", you get quite a few hits......
.........................

Posted Jan 22, 2007, 0:51 AM
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