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 Proteoglycans of nerve cells [View Printable]
R Bishop

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Does anyone know if nerve cells express proteoglycans? I m working on a proteoglycan review article.

Rb
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Posted Aug 15, 2006, 15:35 PM
elmarad

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Yes. Nerve cells express proteoglycans:
Purkinje cells, for example express mimecan and chondroadherin, two small leucine-rich proteoglycans.
Reference:
1. Tasheva ES, Ke A, Conrad GW.
Analysis of the expression of chondroadherin in mouse ocular and non-ocular tissues.
Mol Vis. 2004 Aug 18;10:544-54.

Please see also :
Nakanishi K, Aono S, Hirano K, Kuroda Y, Ida M, Tokita Y, Matsui F, Oohira A.
Identification of Neurite Outgrowth-promoting Domains of Neuroglycan C, a Brain-specific Chondroitin Sulfate Proteoglycan, and Involvement of Phosphatidylinositol 3-Kinase and Protein Kinase C Signaling Pathways in Neuritogenesis. J Biol Chem. 2006 Aug 25;281(34):24970-8

an references therein.


Good luck!
.........................

Posted Aug 30, 2006, 1:26 AM
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