4th Annual
RNA Interference
siRNA and miRNA as Translational Regulators, Functional Genomics Tools, and Therapeutic Agents
June 19-21, 2006 at the Fairmont Hotel, San Francisco, California
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Click here to register or go to
https://commerce22.datapipe.com/chidb/2006/byg/reg.asp Click here to download the RNAi final brochure (no form required)
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Coverage Includes:
Workshop: miRNA in Cancer
Workshop: Optimizing RNAi Delivery
RNAi Screening for Target Discovery/Validation
RNAi Screening of Kinases
RNAi in Animal Models
RNAi Therapeutics
RNAi Technology Showcase
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Monday, June 19
8:00 - 12:00 Registration for Pre-Conference Workshop
Pre-Conference Workshop (separate registration required)
microRNA in Cancer
9:00-9:15 Chairperson_s Opening Remarks
Dr. Michael T. McManus, Assistant Professor, Department of Microbiology and Immunology, UCSF Diabetes Center, University of California, San Francisco
9:15-9:45 Lessons from the microRNA - Chronic Lymphocytic Leukemia Connection: New Paradigms in Molecular Oncology
Dr. George Calin, Research Assistant Professor, Molecular Virology, Immunology & Medical Genetics Department, Ohio State University
9:45-10:15 microRNAs as Novel Targets for Cancer Therapy
Dr. C. Frank Bennett, Senior Vice President, Research, Isis Pharmaceuticals
10:15-10:35 Coffee Break
10:35-11:05 microRNAs in Cancer and Development
Dr. Aurora Esquela Kerscher, Postdoctoral Fellow, Frank Slack Lab, Department of Molecular, Cellular & Developmental Biology, Yale University
11:05-11:35 microRNAs-Based Diagnostics in Cancer A New Approach
Prof. Zvi Bentwich, Chief Scientist, Rosetta Genomics LTD
11:35-1:00 Lunch on Your Own
1:00-1:30 miRNAs as Diagnostic Analytes and Therapeutic Intervention Points
Mr. David Brown, Director of Discovery, Asuragen, Inc.
1:30-2:00 Oncogenic microRNAs: The Gentle Balance between Development and Disease
Dr. J. Michael Thomson, Postdoctoral Research Associate, The Hammond Lab, Department of Cell & Developmental Biology, College of Medicine, University of North Carolina
2:00-2:30 microRNA Profiling using
qPCR Arrays
Dr. Chris Raymond, Research Fellow, Merck Research Laboratories
2:30-3:00 Panel Discussion with the Speakers
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Monday, June 19
8:00 - 12:00 Registration for Pre-Conference Workshop
Pre-Conference Workshop (separate registration required)
Optimizing RNAi Delivery
12:00-12:10 Chairperson_s Opening Remarks
Part I: RNAi Off-Target Effects
12:10-12:40 Widespread _Off-Target_ Silencing Mediated by Sequence Complementarity to the Seed Regions of siRNAs and shRNAs
Ms. Julja Burchard, Senior Research Associate, Biology, Rosetta Inpharmatics LLC
12:40-1:10 Predicting Off-Target Effects in Genome-Wide Screening Programs
Dr. Irene Nooren, Associate Director, Bioinformatics, BioFocus plc
1:10-1:30 Coffee Break
Part II: Novel RNAi Delivery Approaches
1:30-3:00 Speakers to be Announced
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MAIN CONFERENCE
Monday, June 19
12:00 - 4:00 Conference Registration
4:00 - 6:15 Beyond Genome Plenary Session
Top Ten Opportunities in the Post-Genome Era
6:15 - 7:30 Opening Reception in the Exhibit Hall
Tuesday, June 20
7:00 am Registration
7:30 - 8:15 Breakfast Technology Workshop Sponsored by QIAGEN
RNAi Technology and Genome-Wide Expression Profiling - Assessment of Specificity and Pathway Analysis
Dr. Jie Kang, Vice President, R&D, QIAGEN
RNAi SCREENING FOR TARGET DISCOVERY/VALIDATION
8:30 - 9:00 Functionalizing the Druggable Genome using Lentiviral-Based RNAi
Dr. Anthony Orth, Gene Core Group Leader, Division of Genomics, Genomics Institute of the Novartis Research Foundation
9:00 - 9:30 Identification of New Oncology Drug Targets using Loss of Function Genetic Screens of Focused and Genome Scale siRNA Libraries
Dr. Steven R. Bartz, Research Fellow, Rosetta Inpharmatics, A wholly owned subsidiary of Merck & Co., Inc.
9:30 - 10:00 Identification of Novel Genes in the IL-13 Signaling Pathway by siRNA Library Screening
Dr. Michael R. Bowman, Principal Scientist, Inflammation/Respiratory Disease, Wyeth Research Corporation
10:00-11:00 Coffee Break with Poster and Exhibit Viewing
RNAi Screening of Kinases
11:00 - 11:30 Lentivirus-Mediated RNAi Screening
Dr. Richard Klinghoffer, Research Fellow, Cancer Biology, Rosetta Inpharmatics, A wholly owned subsidiary of Merck & Co., Inc.
11:30 - 12:00 High-Throughput shRNA Screens for Essential Kinases Identify Novel Candidates for Cancer Drug Development
Dr. Dorre Grueneberg, Lecturer, Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
12:00 - 12:30 Speaker to be Announced
12:30-2:30 Luncheon Technology Showcase
2:30 - 4:00 Beyond Genome Plenary Session:
Top Ten Opportunities in the Post-Genome Era
4:00-5:00 Refreshment Break with Poster and Exhibit Viewing
RNAi in Animal Models
5:00 - 5:30 Viruses Designed to Combat Other Viruses: The Use of RNAi in Animal Models of Human Disease
Dr. Mark A. Kay, Professor, Departments of Pediatrics and Genetics, Stanford University
5:30 - 6:00 RNAi/Antisense-Based Drug Target Validation in Vivo
Dr. William L. Wishart, Senior Research Investigator, Genome and Proteome Sciences, Novartis Institutes for BioMedical Research
6:00 - 6:30 Transgenic RNA Interference in Mice
Dr. Pumin Zhang, Assistant Professor, Department of Molecular Physiology and Biophysics, Baylor College of Medicine
6:30 Close of Day
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Wednesday, June 21
7:00 am Registration
7:30 - 8:15 Technology Workshop
(Sponsorship Available. For more information, please contact Carol Dinerstein at 617-630-1371 or dinerstein@healthtech.com)
8:30 - 10:00 Beyond Genome Plenary Session
Top Ten Opportunities in the Post-Genome Era
10:00-11:00 Coffee Break with Poster and Exhibit Viewing
RNAi Technology Showcase
11:00-11:30 Optimized Target Identification: Leveraging Ingenuity Pathways Analysis (IPA) with RNAi to Elucidate Pathways for Potential Drug Targets and to Assess Genome-Wide Effects of the Knockdown of a Selected Target
Mr. Arthur Okamoto, Product Manager, Ingenuity Systems Inc.
11:30-11:45 RNAi Goes Genomic: Elucidating Gene Function with siRNA Libraries
Dr. David Dorris, Senior Director & GM, RNAi Technologies, Ambion, An Applied Biosystems Business
11:45-12:00 Off-Target Silencing by RNAi are Associated with Hexamer Matches But Not Overall Identity
Dr. Devin Leake, Senior Scientist, Biology R&D, Dharmacon Inc.
12:00-12:15 Cogenics Speaker to be Announced
12:15-12:30 Additional Sponsorship Available. Contact Carol Dinerstein at 617-630-1371 or dinerstein@healthtech.com.
12:30-2:00 Technology Workshop or Lunch on Your Own
(Sponsorship Available. For more information, please contact Carol Dinerstein at 617-630-1371 or dinerstein@healthtech.com)
RNAi Therapeutics
2:00 - 2:30 RNAi Treatment for HIV Infection: Progress and Challenges
Dr. John Rossi, Professor & Chair, Division of Molecular Biology, Beckman Research Institute, City of Hope
2:30 - 3:00 Speaker to be Announced
3:00 - 3:30 Speaker to be Announced
3:30-4:00 Refreshment Break with Poster and Exhibit Viewing (Last Chance to View)
RNAi Therapeutics for Cancer
4:00 - 4:30 Cancer Immunotherapy Using RNAi Technology
Dr. T. C. Wu, Professor, Departments of Pathology, Oncology, Obstetrics and Gynecology and Molecular Microbiology and Immunology, The Johns Hopkins Medical Institutions
4:30 - 5:00 iRNA Anti-angiogenesis Therapeutics Enhance Bevacizumab (Avastin) Treatment of Colorectal Cancer in Xenograft Tumor Model
Dr. Martin Woodle, CSO & Founder, Intradigm Corp.
5:00 Close of Conference
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Part of Beyond Genome 2006
Gain access to 9 track of Beyond Geonome...Network with over 1,000 participants
15th Annual Bioinformatics...
Biomarker Data Analysis
2nd Annual
Translational Research
10th Annual Proteomics...
Unraveling the Human Proteome
Inaugural West Coast
Target Validation
4th Annual
RNA Interference
Inaugural
Cancer Genomics and Proteomics
Annual Systems Biology...
Pathway and Disease Modeling
Inaugural
Personalized Medicine
2nd Annual
Genomic Biomarkers
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Sponsorship and Exhibit Information
Showcase your company's expertise, brand your solutions and develop revenue opportunities with 1000+ qualified decision-makers
by becoming an Exhibitor or Sponsor of Beyond Genome 2006. Technology Workshops Present your technology to delegates with
a 15-30 minute talk, choose a breakfast or lunch time.
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Place your corporate logo on the final conference brochure, event Web site, conference CD, Program Guide, and signage on site. Packages include exhibit space, conference registrations, use of pre, and post conference mailing lists (through third party vendor) and cooperative mailing to your best prospects.
Focus Group and Invitation-Only Functions
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