Dear Colleague,

There are less than two weeks left to sign up to attend the 2nd Annual Metabolic Diseases World Summit on May 18-21, 2006 taking place in Long Beach, CA. Pioneers in the field will present on novel research and data in metabolic diseases at this four-day summit. We would like to invite you to preview a sample of the talks which will talk place during the event. The PDF file will be available for viewing or downloading until May 10th. Please visit http://www.gtcbio.com/previews/MetabolicPreview.pdf for your copy. The agenda is also available online at http://gtcbio.com/program.asp?cid=17.

PRESENTERS INCLUDE:

Doug Greene, Ph.D., Keynote Speaker, Vice President, Corporate Regulatory Affairs, Head, Regulatory Development Department, SANOFI-AVENTIS

Richard Ho, Ph.D., Head, Medical Informatics, Johnson & Johnson Pharmaceutical R&D
Peer Jacobson, Ph.D., Project Leader, Metabolic Disease Research, Abbott Laboratories
Joseph S. Grimsby, Ph.D., Sr. Research Leader, Metabolic Diseases, F. Hoffmann-La Roche

Ming Wang, M.D., Department of Metabolic Disorders, Amgen Inc.
David Erbe, Ph.D., Cardiovascular and Metabolic Diseases, Wyeth Research
Lori Gowen Morton, Staff Scientist, Regeneron Pharmaceuticals

Rolf Thierringer, Department of Cardiovascular Diseases, Merck Research Laboratories
John Holcombe, M.D., Medical Fellow, US Diabetes Care, Eli Lilly & Company
Anne Reifel Miller, Ph.D., Eli Lilly & Company

Daniel J. Wilson, M.D., Director, Regional Medical Research Specialist Cardiovascular, Pfizer Inc.
David G. Parkes, Ph.D., Senior Director, Research, Amylin Pharmaceuticals
John P. Mayer, Ph.D., Eli Lilly & Company

Wick Johnson, Ph.D., Director, Licensing and Development, Pfizer Incorporated
Linda Egger, Ph.D., Assoc. Director, Scientific Liaison, External Scientific Affairs, Merck & Co., Inc.
Robert Mashal, President & CEO, Alinea Pharmaceuticals

Harold Wright, Director, Biology, CytRx Corporation
Dan Einhorn, Head, Scripps Whittier Diabetes Institute
John Gerich, M.D., Clinical Research Center, University of Rochester School of Medicine

Paresh Dandona, M.D., Professor of Medicine, University of Buffalo
David Bell, M.D., Endocrinologist, University of Alabama at Birmingham School of Medicine
Grant Barish, M.D., Howard Hughes Medical Inst., Gene Expression Lab, Salk Inst. for Biological Studies

Lois Jovanovic, Sansum Diabetes Research Institute
Jean Claude Desmangles, Creighton University
John Rodzvilla, M.D., Auxilium Pharmaceuticals

Marc Rendell, M.D., (Conference Chair) Creighton University School of Medicine
Joel Ray, M.D., Assist. Prof. & Clinician Scientist, Div. of Endo. & Met., University of Toronto
Bernice Welles, M.D., MBA, VP, Development, DiObex

To register, visit www.gtcbio.com or call 626-256-6405.

Other Upcoming Conferences:

Assay Development & High-throughput Screening
June 22-23, 2006 - San Francisco, CA

Therapeutic Strategies against Neurodegenerative Conditions
September 18 & 19, 2006

Epigenetic and Neural Development Disorders
September 18 & 19, 2006

Partnering, Licensing & Alliance Management for Neuro-focused Organizations
September 19th, 2006

3rd Annual Tumor Progression & Therapeutic Resistance
Oct 22-24, 2006 - Baltimore, MD

Immunodiagnostic and Immunomonitoring: From Research to Clinic
November 5-7, 2006 - San Diego, CA

4th conference on Vaccines: All Things Considered
November 16-17, 2007 - Washington DC

2nd Modern Drug Discovery & Development Summit
December 4-6, 2006 - Pennsylvania Convention Center, Philadelphia, PA
This summit will including the following 11 conferences:
1. Systems Biology in Drug Discovery
2. Model Organisms in Drug Discovery
3. CNS Diseases and Drug Discovery
4. Nanobiotechnology in Drug Discovery
5. Antibodies Discovery and Development
6. Drug Delivery Technology
7. Medicinal Chemistry
8. Epigenetic Cancer Therapy
9. Stem Cell Research and Regenerative Medicine
10. Drug Safety and Pharmacovigilance
11. Biotech and Pharmaceutical Licensing and Deal-Making

Visit www.gtcbio.com for details.