PhD Position
(Bilbao, Spain)
4-year FPI contract associated to MCINN
Grant CTQ2011-28680
Topic: Recognition of
chromatin structure by the ING
tumor suppressors
Where: At CIC bioGUNE, near Bilbao, Spain, under the supervision of Dr. Francisco J. Blanco, Group leader in the Structural
Biology Unit
Who: A motivated graduate student with interest in structural
biology.
When: The contract will commence in summer 2012. By then the student should hold a Master degree to have access to the PhD program of a Spanish university
How: Early in 2012 the MCINN will publish the list of
grants with associated contracts and the candidate should apply for it.
If the candidate is currently enrolled in a university Master program he/she may do the Master research project in our laboratory starting in January 2012.
Recent publications of the group
• The Dimeric Structure and the Bivalent Recognition of H3K4me3 by the
Tumor Suppressor ING4 Suggests a Mechanism for Enhanced Targeting of HBO1 Complex to
Chromatin. Alicia Palacios et al., 2010, Journal of
Molecular Biology 396, 1117-1127.
• Functional impact of
cancer-associated mutations in the
tumor suppressor
protein ING4. Alberto Moreno et al., 2010, Carcinogenesis 31, 1932-1938.
• Solution Structure of Human Growth Arrest and
DNA Damage 45α (Gadd45α) and its
Interactions with Proliferating
Cell Nuclear
Antigen (PCNA) and Aurora A
Kinase. Ricardo Sánchez et al., 2010, Journal of Biological Chemistry 285, 22196-22201.
• Transient
Protein-
DNA/
RNA interactions. Francisco J Blanco & Guillermo Montoya, 2011, FEBS Journal 278, 1643-1650.
• Reduced stability and increased dynamics in the human proliferating
cell nuclear
antigen (PCNA) relative to the
yeast homolog. Alfredo De Biasio et al., 2011, PLoS One 6, e16600.
Interested candidates please email a cover letter, your CV, and names (including email address) of at least two referees to rrhh@cicbiogune.es with ref. 3101 in the subject.
Deadline: Contact employer
For more details