Award
 Refer a Friend  Bookmark us  Link To Us  Home
 
Solutions Search! The Customized Life Science Search Engine
Search Site
Search Suppliers
Search Internet
Search over 6000 life science websites specifically selected by our expert scientist moderators.

Other Topics
8/9/2007 05:55 AM
6/6/2006 02:26 PM
11/13/2004 12:07 AM
Subscribet to topic
bottom of page RSS Feed Topic Feed
 orphan receptors [View Printable]
DaJo

Frog Egg

Avatar of DaJo





Group: Member
Posts: 16
Joined: Nov 10, 2004







 Send a personal messsage to DaJo Reply with a quote from this post Go to the top of the page

Is there an online resource with information on all orphan receptors or those orphan receptors of the TNF superfamily members? If not good review publications with this information?
.........................

 Posted Nov 13, 2004, 0:49 AM
Big E

Tadpole

Avatar of Big E





Group: Member
Posts: 32
Joined: Oct 08, 2004







 Send a personal messsage to Big E Reply with a quote from this post Go to the top of the page

Good Question
Most of the studies on Orphan receptors seems to concentrate on nuclear receptors or G protein coupled receptors, I am also interested in novel TNF family members the family is up to 19 ligand members that signal through 29 receptors. I'm sure there are more ligands and receptors out there. I will keep a look out for articles on new TNF family members.
.........................

Posted Jan 27, 2005, 6:17 AM
RH

Tadpole

Avatar of RH





Group: Member
Posts: 26
Joined: Mar 16, 2005







 Send a personal messsage to RH Reply with a quote from this post Go to the top of the page

Does anyone know a good book about TNF-a pathway?
.........................

Posted Mar 29, 2005, 5:52 AM
samm

Frog Laureate

Avatar of samm
See
Similar
Scientists



View Blogs


Group: Moderators
Posts: 363
Joined: Mar 03, 2005







 Send a personal messsage to samm Reply with a quote from this post Go to the top of the page

Try the "Cytokine Handbook" - its a two volume, cross referenced book on cytokines and chemokines. Also, an online resource is COPE (with cytokines!).
.........................

Posted Mar 29, 2005, 20:02 PM
vanishing

Frog Laureate

Avatar of vanishing
See
Similar
Scientists





Group: Member
Posts: 132
Joined: Apr 25, 2005







 Send a personal messsage to vanishing Reply with a quote from this post Go to the top of the page

Here are some reviews on this subject:

1.) Blumberg and Evans
Genes and Development, Vol. 12, No. 20, pp. 3149-3155, October 15, 1998
Orphan nuclear receptorsnew ligands and new possibilities

http://www.genesdev.org/cgi/content/full/12/20/3149

2.) A little out-dated:
Wilson et al., 1998 Orphan G-protein-coupled receptors: the next generation of drug targets?
British J. of Pharmacology

3.) That's a newer review
Wise et al., 2004
THE IDENTIFICATION OF LIGANDS AT ORPHAN G-PROTEIN COUPLED RECEPTORS
Annual Review of Pharmacology and Toxicology 44: 43-66

http://arjournals.annualreviews.org/doi/abs/10.1146%2Fannurev.pharmtox.44.101802.121419?cookieSet=1
.........................

Posted May 13, 2005, 21:56 PM
saswati1

Frog Laureate

Avatar of saswati1
See
Similar
Scientists



View Blogs


Group: Moderators
Posts: 170
Joined: Mar 22, 2006







Reply with a quote from this post Go to the top of the page

Liu ZG. Related Articles, Links
Molecular mechanism of TNF signaling and beyond.
Cell Res. 2005 Jan;15(1):24-7. Review.
PMID: 15686622 [PubMed - indexed for MEDLINE]
.........................

Posted Mar 30, 2006, 20:22 PM
top of page

Forum Jump