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orphan receptors [View Printable]
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DaJo
Group: Member Posts: 16 Joined: Nov 10, 2004
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Is there an online resource with information on all orphan receptors or those orphan receptors of the TNF superfamily members? If not good review publications with this information?
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Posted Nov 13, 2004, 0:49 AM |
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Big E
Group: Member Posts: 32 Joined: Oct 08, 2004
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Good Question Most of the studies on Orphan receptors seems to concentrate on nuclear receptors or G protein coupled receptors, I am also interested in novel TNF family members the family is up to 19 ligand members that signal through 29 receptors. I'm sure there are more ligands and receptors out there. I will keep a look out for articles on new TNF family members.
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| Posted Jan 27, 2005, 6:17 AM |
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RH
Group: Member Posts: 26 Joined: Mar 16, 2005
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Does anyone know a good book about TNF-a pathway?
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| Posted Mar 29, 2005, 5:52 AM |
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samm
Group: Moderators Posts: 363 Joined: Mar 03, 2005
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Try the "Cytokine Handbook" - its a two volume, cross referenced book on cytokines and chemokines. Also, an online resource is COPE (with cytokines!).
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| Posted Mar 29, 2005, 20:02 PM |
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vanishing
Group: Member Posts: 132 Joined: Apr 25, 2005
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Here are some reviews on this subject: 1.) Blumberg and Evans Genes and Development, Vol. 12, No. 20, pp. 3149-3155, October 15, 1998 Orphan nuclear receptorsnew ligands and new possibilities http://www.genesdev.org/cgi/content/full/12/20/31492.) A little out-dated: Wilson et al., 1998 Orphan G-protein-coupled receptors: the next generation of drug targets? British J. of Pharmacology 3.) That's a newer review Wise et al., 2004 THE IDENTIFICATION OF LIGANDS AT ORPHAN G-PROTEIN COUPLED RECEPTORS Annual Review of Pharmacology and Toxicology 44: 43-66 http://arjournals.annualreviews.org/doi/abs/10.1146%2Fannurev.pharmtox.44.101802.121419?cookieSet=1
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| Posted May 13, 2005, 21:56 PM |
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saswati1
Group: Moderators Posts: 170 Joined: Mar 22, 2006
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Liu ZG. Related Articles, Links Molecular mechanism of TNF signaling and beyond. Cell Res. 2005 Jan;15(1):24-7. Review. PMID: 15686622 [PubMed - indexed for MEDLINE]
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| Posted Mar 30, 2006, 20:22 PM |
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