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 Glycosylated soluble receptors [View Printable]
LabDweller

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 Send a personal messsage to LabDweller Reply with a quote from this post Go to the top of the page

I need to test the ability of different human NGFb mutants to bind to its cognate receptors, p140TrkA and NGFR. I was thinking of trying co-pulldown studies using recombinant human TrkA-Fc and NGFR-Fc to pulldown different mutant NGFb proteins. Several articles have indicated that glycosylation of these receptors affect their activity. I was wondering whether anyone knows a good source of glycosylated human p140TrkA-Fc and NGFR-Fc?
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 Posted Jan 11, 2006, 2:35 AM
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