Herpes simplex virus can infect neurons, are there other viral vectors that can infect nondividing neuronal cells. If not what are the best HSV viral expression systems available for transduction of neurons?

Big E said:

Herpes simplex virus can infect neurons, are there other viral vectors that can infect nondividing neuronal cells. If not what are the best HSV viral expression systems available for transduction of neurons?

HSV, Lentivirus and AAV can all be used for the transduction of neuronal cells. I suggest using HSV amplicons vectors to eliminate the large HSV viral genome.
These pubs should help in your decision making.

J Virol.1997 September;71(9): 66416649.
Highly efficient and sustained gene transfer in adult neurons with a lentivirus vector.

J Gene Med. 2004 Sep;6(9):951-62.
Lentiviral vectors for treating and modeling human CNS disorders.

Exp Physiol. 2004 Nov 12;
Promoters and serotypes: targeting of AAV vectors for CNS gene transfer in vitro and in vivo.

Gene delivery using herpes simplex virus vectors.
DNA Cell Biol. 2002 Dec;21(12):915-36

Int J Exp Pathol. 2004 Oct;85(4):177-90.
Herpes simplex virus-based vectors.

The problem with lentiviral vectors is their poor replication in non-dividing cells. Otherwise, they are my choice of vector.

Herpes Virus Vectors would definatly be a good option.

AAV vectors infect neurons and are associated with very low immunogenicity. There are at least 8 serotypes to choose from and if you need quick expression without having to wait for the vector to replicate and your transgene is small enough then go for a "self-complementary" (scAAV) or "double-stranded" (dsAAV) vector. These are the state of the art for now.