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THE PLASMA PROTEOME: High Abundance Vs. Low Abundance
Discovering Biological Markers for Diagnostics and Drug Discovery

January 10-11, 2006 | Hotel Del Coronado | San Diego, CA
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Kick Off Keynote Presentation

Challenges in the Analysis of Complex Specimens
Dr. John R. Yates, III, Professor of Cell Biology, Scripps Research Institute


Challenges of High Abundance Plasma Proteins

Highlights of the HUPO Plasma Proteome Project
Dr. Gilbert S. Omenn, Professor of Internal Medicine, Human Genetics, and Public Health, University of Michigan,
Leader, HUPO Plasma Protein Project

Serum Proteomic Standards
Dr. Peter E. Barker, Principal Investigator & Biologist, NIST

Blood Samples for Proteomics: Don't Overlook Step One of Plasma Proteomics
Dr. Craig Gelfand, Director, Growth Technologies, Preanalytical Systems, BD Biosciences

Digging Deeper into the Proteome

Peptidomics Approaches for Low-Abundance Biomarker Detection in Blood Plasma from Clinical Trials
Dr. Peter Schulz-Knappe, Chief Scientific Officer, BioVisioN AG

Integration of Combinatorial Chemistry and Affinity Chromatography Provides a Powerful Platform for
Proteomics and New Product Discovery
Dr. David J. Hammond, Executive Director Plasma Derivatives, Holland Laboratory, American Red Cross

Development of a "Reverse Capture" Microarray for Studies of Antigen-Autoantibody Reactivity
Dr. Brian Liu, Assistant Professor, Urology, Brigham and Women's Hospital, Harvard Medical School

Biomarker Discovery

Candidate-Based Approach to Biomarker Development
Dr. N. Leigh Anderson, Chief Executive Officer, Plasma Proteome Institute

Clinical Plasma Profiling to Identify and Sequence Proteins that Differentiate Anti-Hypertensives
Dr. Gregory J. Opiteck, Director, Protein Analysis, Caprion Pharmaceuticals, Inc.

CSF and Plasma-Based Protein Biomarkers for Motor Neuron Disease
Dr. Robert Bowser, Associate Professor, Pathology, University of Pittsburgh

The Plasma Proteome in Sepsis: Toward Dynamic, Data-Driven Disease Management
Dr. Stephen F. Kingsmore, President, National Center for Genome Resources

A Novel Platform for Serum Biomarker Discovery and Validation for Application in Cancer Diagnosis
Mr. David Deems, Vice President, Product Integration and Operations, Predicant Biosciences

Towards Comprehensive Proteomic Mapping of Blood Vessels through Prefractionation and Multi-modal
MS Analysis
Dr. Jan E. Schnitzer, Scientific Director, Professor of Cellular & Molecular Biology, Director of Vascular Biology &
Angiogenesis Program, Sidney Kimmel Cancer Center

Identification of Proteotypic N-linked Glycopeptides for Serum Biomarker Discovery
Dr. Hui Zhang, Senior Research Scientist, Serum Biomarker Discovery Group, Institute for Systems Biology

HUPO Initiatives for Biomarker Discovery: Opportunities and Challenges
Dr. Samir Hanish, Director, Molecular Diagnostics Program; Member, Fred Hutchinson Cancer Research Center
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Corporate Sponsors:

Beckman Coulter Inc.
Bruker Daltonics
Biacore
Decision Biomarkers
GenTel
INCAPS
Invitrogen
Nautilus Biotech
NextGen Sciences
Nonlinear Dynamics
Pall Life Sciences
Promega Corporation
QIAGEN, Inc.
Whatman

For Sponsorship and Exhibit Information contact:
Arnold Wolfson at 617-630-1331 or awolfson@healttech.com
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