I was at a convention recently and several manufacturers presented the chip technology which will be availabe in 2005. Has anyone used this technology? Is it usable for clinical laboratory? The application may be viral detection, antidody detection, transplantation, etc.

Nikaein said:

I was at a convention recently and several manufacturers presented the chip technology which will be availabe in 2005. Has anyone used this technology? Is it usable for clinical laboratory? The application may be viral detection, antidody detection, transplantation, etc.

The chip technology is available by many companies:
1-Sartorius has HIV genotyping kits by chip technology.
2-Affimetrix has DNA-chip technology,
3-IVD Technology has DNA-microarray genome chip,
4-Purdue and PerSeptive Biosystem, Inc. of Boston are developing a technology called: doing chemistry on a chip or miniature laboratories,
5-the project Genomics for kidney transplant will use proteomic chip technology,
6- there is fully automated chip-based nanoelectrospray tandem mass spectrometry available in the market.

Since we're on the Immunity/Transplantation forum, I'm going to guess that what you saw is a new Dynal method of microarray-based antibody detection. HLA proteins on an array instead of beads or microwell plates. If memory serves, the assay is based on an array technology developed by a German company called CLON-DIAG. I have not personal experience with this assay.

At the recent Canadian Society of Transplantation meeting someone was showing an array-based genetic typing method for HLA. Innogenetics I think. Not really my area, but HLA typing, especially high-resolution, seems like a natural app for array technology.