Anybody has any information about a possible relationship?

Involvement of tumor suppresor genes in neurodegenerative disorders?

It is my hypothesis that all tissues rely on DHEA for optimal function. It is also my hypothesis that low DHEA may trigger cancer formation (Annals of Internal Medicine 2005; 142: 471-472). However, once started, cancer, like other tissues, also relies on DHEA for function. Since neurodegeneration may be caused by low DHEA, cancer may cause neurodegeneration when cancer uses DHEA at the expense of the rest of the body. I think cachexia, often found with cancer, is caused by this use of DHEA by cancer. This often includes some form of neuropathy.

Very interesting... moreover, hormones act through nuclear receptors, which raises the issue of an abnormal regulation of transcription. Thanks