Reversal potential and Equilibrium potential http://www.scientistsolutions.com/t19417-reversal+potential+and+equilibrium+potential.html Life Science Discussion en-us sci7feed@sci7.nojunkorherepleasespam.com hourly 1 2005-05-05T12:00+00:00 Reversal potential and Equilibrium potential http://www.scientistsolutions.com/t19417-reversal+potential+and+equilibrium+potential.html I've recorded Na+ currents from neurons and I'm trying to fit activation and steady-state deactivation curve.
External sodium conc. was 127mM and internal was 8.6 mM.
ENa is 67.8 mV predicted by the Nernst equation
but actual extrapolated reversal potential was near +42 mV
This deviation possibly arose from contamination outward currents or non-linearity arising form Goldman-type rectification.
Here is my question.
When I fit the activation curve, w...]]> Fri, 01 Jul 2011 11:07:59 GMT