Giant brown cells among the lymphocytes http://www.scientistsolutions.com/t15987-giant+brown+cells+among+the+lymphocytes.html Malignant cells, melanophages or? Life Science Discussion en-us sci7feed@sci7.nojunkorherepleasespam.com hourly 1 2005-05-05T12:00+00:00 Giant brown cells among the lymphocytes http://www.scientistsolutions.com/t15987-giant+brown+cells+among+the+lymphocytes.html It might actually be T cell 'activation clusters' (T cells can function as weak +ve and moderate -ve (tolerogenic) APCs in T-T interactions) especially if they are in rounded bottom plates (or high enough density in flat bottom plates) - you see that with PMA+I stimulation. However, it can also be cell fragments or some form of contamination - hence, the D...]]> Mon, 27 Sep 2010 16:29:25 GMT Giant brown cells among the lymphocytes http://www.scientistsolutions.com/t15987-giant+brown+cells+among+the+lymphocytes.html Vitting]]> Sun, 26 Sep 2010 04:55:58 GMT Giant brown cells among the lymphocytes http://www.scientistsolutions.com/t15987-giant+brown+cells+among+the+lymphocytes.html Can you help me identify the type of cells seen in this picture?
I'm establishing cultures of T-cells from tumour fragments (melanoma patients). Sometimes we see some large dark cells around the tumour fragment and among the proliferating lymphocytes. They typically appear after a couple of weeks of culturing and then later seem to die out - or at least they are totally outnumbered by the proliferating T-cells.
Some of my colleagues ...]]> Sun, 26 Sep 2010 04:50:06 GMT