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Identifying biomarkers that are specific for certain pathological conditions is critical for developing disease- selective imaging probes. Anionic charges are exposed on the surface of numerous partic
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Whole-animal fluorescence imaging is often complicated by the attempt to determine the anatomical location of a given fluorescent signal. When multiple fluorophores are present, this task is even more
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CCD cameras are widely used to capture chemiluminescent images of Western blots and ELISAs (enzyme-linked immunosorbent assay). ELISAs are used as a diagnostic tool to determine the concentration of a
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An X-ray image provides a convenient anatomical map of musculoskeletal features that is useful for co-registration of optical or radioisotopic signals.
X-ray is an orthogonal imaging modality that w
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Molecular imaging, or the non-invasive spatial and temporal detection of signatures within the intact living organism that relate to cellular and intracellular events, has become essential for assessi
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Cap analysis gene expression (CAGE) is a method to identify the 5' ends of transcripts, allowing the discovery of new promoters and the quantification of gene activity. Combining promoter location and
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The study of organogenesis in mammals allows investigation of a wide variety of basic cell biological processes in the context of the intact organ. This has become especially important in the age of g
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PET/SPECT cylindrical phantom is oftenlly used in Nuclear Medicine Technology for Quality Assuarance of Scaning Devices,
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The Caenorhabditis elegans embryo is particularly amenable to microscopy and embryological studies because of its short developmental time, transparent shell, and nonpigmented cells. The agar mount de
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Cell movements in the pregastrulation egg cylinder mouse embryo play an important role in patterning. The stereotypic movement of the anterior visceral endoderm converts a proximal-distal axis to an a
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