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Motor cortex cytoarchitecture


Posted 6/29/2009 4:52:45 AM

I want to do morphological studies of motor cortex in rat brain. I have got Paxinos atlas with me but still need to segregate the various neurons according to their shapes, sizes and also types. Can anyone suggest me some atlas or literature from where I can get this information?


Posted 6/29/2009 5:03:18 AM

Please read this article, I think that would be sufficient for your study. In case you need another help please ask here again.

Donoghue JP, Wise SP. 1982 The motor cortex of the rat: cytoarchitecture and microstimulation mapping. J Comp Neurol.; 212(1):76-88.


There at pubmed, you can find this abstract as I am getting directly form the link


The first motor (MI) cortex of the rat was identified as the region from which movements could be evoked by the lowest intensity of electrical stimulation. The location of this region was correlated with cytoarchitecture in the frontal and parietal cortex. Two frontal areas can be discerned in Nissl-stained sections: (1) the medial agranular field, marked by a pale-staining layer III and a compact layer II, and (2) the lateral agranular field, which has more homogeneous superficial layers and a broad layer V containing large, densely staining cells. Both of these regions project to the spinal cord and can therefore be included in the somatic sensorimotor cortex. MI in the rat coincides with the lateral agranular field but also overlaps with part of the adjacent granular cortex of the first somatic sensory (SI) representation. We conclude that the rat MI cortex can be identified by microstimulation techniques and by cytoarchitecture in the rat.

PMID: 6294151 [PubMed - indexed for MEDLINE]




Posted 7/10/2009 2:22:03 AM
there are now web atlas search rat brain atlas in google click on first two site you will find a virtual brain atlas with various features

Posted 7/30/2009 4:00:12 PM
Brecht M, Krauss A, Muhammad S, Sinai-Esfahani L, Bellanca S, Margrie TW (2004) Organization of rat vibrissa motor cortex and adjacent areas according to cytoarchitectonics, microstimulation, and intracellular stimulation of identified cells. J Comp Neurol 479: 360-373.

Check out this article. Also, use thionin stain (as opposed to CO). It just looks nicer. :)

Posted 7/31/2009 12:57:05 AM
Dear Shamba,

Here useful Article for your reference,

The effect of motor cortex stimulation in deafferentated rats,

Robert Rusina, Simon Vaculin, Anna Yamamotova, Stephan Barek, Helena Dvorakova & Richard Rokyta.