Scientist Job - In-Vivo Pharmacology/Oncology - Waltham, Ma, U.S.

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Matthew Masterson
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Scientist Job - In-Vivo Pharmacology/Oncology - Waltham, Ma, U.S.

Description:
Seeking a highly motivated and experienced in vivo scientist to join the Oncology research team. The successful candidate will independently design and execute in vivo studies to evaluate new drug candidates in the Oncology portfolio. This will include developing and characterizing mouse models of cancer, running in vivo screening cascades to support lead optimization, and establishing PK/PD/Efficacy relationships in appropriate models to support translation to the clinic. The candidate will work as part of a multi-discipline project team to generate, analyze and communicate data to colleagues and key stakeholders.

Requirements:
Qualifications
* PhD in Pharmacology or related discipline, with 0-2 years post doctoral experience, or an MS with a minimum of 5-7 years relevant experience, preferably in an industry setting.
* Experience in developing and characterizing mouse models of cancer is critical.
* Experience and strong working knowledge of in vivo pharmacology techniques required, including preparation of test compounds, handling and dosing mice, and collection of blood and tissues for PK and PD biomarker analysis.
* Familiarity with pharmacology concepts, including establishing PK/PD relationships from in vitro and in vivo assays, and generating human dose predictions for clinical development.
* Experience with sterile tissue culture, and with basic molecular and cellular biology techniques required.
* Familiarity with advanced models of cancer including primary patient models would be an advantage.

Apply here: http://www.hirelifescience.com/seeker_jobs.aspx?jobsID=429111&jobtitle=Scientist - In-Vivo Pharmacology/Oncology

eayyub
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eayyub
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&nbsp;Hi There,<br /> I'm

&nbsp;Hi There,<br /> I'm highly interested in the job posted on the scientist solutions site. I have more than16 years experience in pharmacology invivo and cancer research supporting and enhancing drug discovery and development. I worked at different levels of Rand D to GMP environment and have really good hands in animal handling, xenografts models forllowing Iacucs laws and techniques reaching the maximum efficacy with minimum adverse effect.&nbsp;In addidition, I have a good knowledge in executing data from PK/PD to design effeicacy study for the desired therapeutic effect and translating results to predict the effective dose and schedule for the second level of clinical phase 1 and 2.<br /> I believe that i'll be a good fit for this position special in highlighting high quality experimental data that will motivate researchers and invistors to participate in our business plan.&nbsp;<br /> <br /> References and recommendations are available up on request.<br /> <br /> Looking forward to hear from you and discuss further this opportunity.<br /> <br /> Sicerely,<br /> Eman Ayyub<br type="_moz" />

eayyub
eayyub's picture
Hi There,

Hi There,
 I'm highly interested in the job posted on the scientist solutions site. I have more than16 years experience in pharmacology in vivo and cancer research supporting and enhancing drug discovery and development. I worked at different levels of R and D to GMP environment and have really good hands in animal handling, xenograft models following IACUC laws and techniques reaching the maximum efficacy with minimum adverse effect. In addition, I have a good knowledge in executing data from PK/PD to design efficacy study for the desired therapeutic effect and translating results to predict the effective dose and schedule for the second level of clinical phase 1 and 2. I believe that I’ll be a good fit for this position special in highlighting high quality experimental data that will motivate researchers and investors to participate in our business plan.
 References and recommendations are available up on request.
 Looking forward to hear from you to discuss further this opportunity.
 Sincerely,
Eman Ayyub
Eman_pharma70@hotmail.com
6179224214