drug screening

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Rajeshwari patel
Rajeshwari patel's picture
drug screening

Hi,
Every one!!!

I want to knoe exct differance between primary screening of the drug and secondary screeing of tha drug
Can any body able to give guidance regarding it

Thanks
Rajeshwari

Biju
Biju's picture
Hi rajeswari

Hi rajeswari
Primary screening involves screening larg nos to select out  candidate small moleculels that are likely to have clinical activity.In secondary screening these molecules will undergo extensive tesing including pharmacokinetics and  pharmacodynamics and also with additional cell lines not used in primary screening.
Biju