Hi, Say hello to all of you. It is my first time to come here. Waa, it is great!
Now I am trying to studying inwardly rectifying potassium channels in chemosensitive neurons. I read one paper titled with "carbon dioxide regulates the tonic activity of locus coeruleus neurons by modulating a proton- and polyamine-sensitive inward rectifier potassium current". I have a question which is how to analyze the traces by subtraction of basal trace from experimental trace? What is the positive or negative slope conductance means ?
Thank you very much!