The U12 splicosome functions in the cytosol

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Jon Moulton
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The U12 splicosome functions in the cytosol

The U12 spliceosome functions in the cytosol, operates through mitosis and is required for zebrafish embryo survival through somitogenesis:
Knig H, Matter N, Bader R, Thiele W, Müller F. Splicing Segregation: The Minor Spliceosome Acts outside the Nucleus and Controls Cell Proliferation. Cell 2007 131:718-29.