After loss of APC, DNA demethylase keeps intestinal cells undifferentiated

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Jon Moulton
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After loss of APC, DNA demethylase keeps intestinal cells undifferentiated

Rai K, Sarkar S, Broadbent TJ, Voas M, Grossmann KF, Nadauld LD, Dehghanizadeh S, Hagos FT, Li Y, Toth RK, Chidester S, Bahr TM, Johnson WE, Sklow B, Burt R, Cairns BR, Jones DA.  DNA demethylase activity maintains intestinal cells in an undifferentiated state following loss of APC.  Cell. 2010 Sep 17;142(6):930-42.