REEP4 needed for nerve and muscle development

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Jon Moulton
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REEP4 needed for nerve and muscle development

Morpholino screen in Xenopus tropicalis identifies a protein needed for nerve and muscle development:
Argasinska J, Rana AA, Gilchrist MJ, Lachani K, Young A, Smith JC. Loss of REEP4 causes paralysis of the Xenopus embryo. Int J Dev Biol. 2009;53(1):37-43.

R Bishop
R Bishop's picture
REEP (Receptor expression

REEP (Receptor expression enhancing protein) family.

REEPs are a little confusing. This article says REEP1 is involved in olfactory sensing

http://news.bio-medicine.org/biology-news-3/Genetic-discovery-paves-way-to-decode-sense-of-smell-in-mammals-13799-2/

This article says REEP1 is localized to the mitochondria and is involved in neurodegenerative disease?

http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=16826527

Rb