how to induce diabetes in rats

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Joaj
Joaj's picture
how to induce diabetes in rats

please,i need to know how to induce diabetes in rats.i am a beginner

g a
g a's picture
Dear Joaj

Dear Joaj
There is a parallel discussion going on in the forum You can check into that.
http://www.scientistsolutions.com/t11072-stz+induced+diabetes+i+rats.html

Jitendra Sinha
Jitendra Sinha's picture
 One can induce diabetes by

 One can induce diabetes by using chemical streptozotocin. Please read these papers, that would give yo a good background of the topic.
http://care.diabetesjournals.org/content/28/2/290.abstract
http://www.journals.elsevierhealth.com/periodicals/nut/article/PIIS0899900700004688/abstract
http://www.springerlink.com/content/j2vqvan765dahpfv/

MUTHUMARIAPPAN ...
MUTHUMARIAPPAN Murugan's picture
Hi Joaj,
Monu
Monu's picture
 Diabetes is of three types

 Diabetes is of three types and if you want to know about making animal model for one, first selct the type which you want to make then you can induce that type. Details can be found at http://en.wikipedia.org/wiki/Diabetes
 
read this article  
Animal models in type 2 diabetes research: An overview at  icmr.nic.in/ijmr/2007/march/0318.pdf