Postdoctoral Scientist in Bioinformatics and Computational Biology

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Postdoctoral Scientist in Bioinformatics and Computational Biology

The Helmholtz Centre for Environmental Research – UFZ is a research institution within the Helmholtz Association. It provides scientific contributions to the safeguarding of the natural basis of life and of human development potentialities for current and future generations under the challenges of global and climate change. In this way the UFZ contributes towards a sustainable development.
The Department of Proteomics is offering a fulltime-position of a
Postdoctoral scientist in bioinformatics and
computational biology (m/f)
(code digit 27/2011)

available for 36 months and starting on the 1st of April 2011.
The research agenda of the Helmholtz Centre for Environmental Research – UFZ is to study the complex interactions between humans and the environment in cultivated and damaged landscapes. Omics data sets (genomics, transcriptomics, epigenetics, proteomics and metabolomics) are increasingly used to analyse model systems. They create a need for specialized data evaluation and integration on the way from data to meaningful interpretation.
The successful candidate will be responsible for the integration and analysis of genomic, transcriptomic, epigenomic, proteomic and metabolomic data sets generated mostly within the UFZ. The focus will lie on supporting researchers in planning their omics experiments, on evaluation of the resulting data, as well as, on developing customized analysis methods and software tools. In order to optimize the results the successful candidate will be involved in planning experiments and evaluation strategies. The analysis will include multivariate data sets, typically from time or concentration series from exposition experiments. A topic of interest is also the analysis of raw mas spectra in proteomics and metabolomics. Another focus will be the identification of involved pathways drawn from transcriptome, proteome and metabolome analyses. Furthermore the integration of different data sets in a systems biology perspective will be part of the work.
The scientist will be working in an exciting and highly interdisciplinary research environment of biologists, chemists, biochemists and bioinformaticians with excellently equipped facilities (proteomics, metabolomics and transcriptomics platforms are established, a transcriptome platform will be added in 2011).
The ideal candidate has a strong background in bioinformatics and computational biology and holds a PhD in computer science, biology, chemistry or physics. Programming experience in a UNIX/Linux environment using programming languages such as Perl, Python, C or C++, is required. Also, experience in multivariate statistical analysis of biological datasets is compulsory, preferably using R and Bioconductor. Experience with relational databases such as MySQL or PostgreSQL, and programming of web applications is desirable.
The applicant should possess a core understanding of genetics and molecular biology, and be familiar with widely used databases and software, including those for analysis of raw spectra in proteomics and metabolomics. In addition, the candidate must have excellent communication and interpersonal skills and be capable of working within an interdisciplinary team. Moreover he/she must have excellent written and verbal skills in English, basic communication skills in German are a plus.
We are searching for a highly motivated, reliable person with a diligent workstyle who is interested in method development and collaborative work.
Salary will be according to the appropriate civil service level TVöD, depending on the personal preconditions up to Entgeltgruppe 14.
The UFZ is an equal opportunity employer; women are explicitly encouraged to apply.
Physically handicapped persons will be favoured if they are equally qualified.
Scientific information can be provided by:
PD Dr. Martin von Bergen, phone +49 341 235-1211, E-Mail:
Dr. Jörg Hackermüller, phone +49 341 235-1561, E-Mail:
Please send your complete application documents until March 5, 2011 under the code digit 27/2011 to the Personnel department of the Helmholtz Centre for Environmental Research, P.O. Box 500136, D-04301 Leipzig, Germany or by E-Mail to

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