The primary goal of the Diabetes, Cardiovascular & Metabolic Diseases Division is to improve prevention and treatment strategies for diabetes, cardiovascular disease, and metabolic disorders including obesity, metabolic syndrome, and endocrine diseases. Understanding the determinants of metabolic diseases will allow us to predict who is at greatest risk of developing diabetes, obesity, and cardiovascular disease, which is the first step toward prevention. Because diabetes, CVD and other metabolic disorders develop long before they are diagnosed, efforts to improve detection strategies are critically needed to decrease morbidity and decrease mortality. For those individuals living with diabetes, CVD, or obesity, more effective therapeutic options will improve the quality and quantity of life in these patients and lessen the risk of developing complications secondary to this disease. The major goal of the Diabetes, Cardiovascular & Metabolic Diseases Division is in complete accord with the guiding mission of TGen to develop earlier diagnostics and smarter treatments.
There are three disease-focused research units within the Diabetes, Cardiovascular &Metabolic Diseases Division which have been created to achieve an enhanced mechanistic understanding of disease process, identify targets for diagnostic and therapeutic treatments, develop improved treatment strategies based on personalized medicine approaches for metabolic diseases, and identify at-risk individuals for prevention strategies. Each research unit will utilize interconnected strategies and tools to identify targets, interpret molecular data and translate results in predictive models,assess functionality, and evaluate clinical value and effectiveness.
Brief Posting Description
A postdoctoral fellow position is available with a focus on diabetes-related disorders. We are looking for a strongly motivated person with a pioneering and innovative spirit. The person will work closely with the principal investigator to advance the research.
We are seeking a postdoctoral researcher to join in the multidisciplinary study of metabolic diseases through the application of molecular genetics, functional genomics, and molecular/cell biology in the Diabetes, Cardiovascular and Metabolic Diseases Division. Qualifications include a doctoral degree in molecular biology, cellular biology, molecular genetics, genetics/genetic epidemiology or equivalent. Applicants with expertise in molecular biology, epigenetic approaches, molecular genetics, expression studies, genetic epidemiology, or related areas are particularly encouraged to apply. A deep understanding of human genetics, epigenetics, functional genomics, and an interest in renal complications of diabetes, obesity, and related metabolic diseases are necessary.
There are several large cardiovascular, liver, and renal disease projects ongoing at TGen. Major foci involve association and epigenetic studies, and global expression profiling to elucidate signature tags associated with disease susceptibility.The DCM Division is committed to accelerating the discovery of predictive biomarkers and effective therapies for the prevention and treatment of a wide variety of metabolic diseases, including diabetes, obesity, and hyperlipidemia. We offer a supportive environment for faculty to participate in these funded studies or develop new projects, in cooperation with other divisions within the institute.
1. Conduct scientifically meaningful and important research to address molecular mechanisms underlying human complex disease, including complications of diabetes, cardiovascular disease, and metabolic disorders; develop and expand an independent research program within the institute; present and publish scientific findings; successfully compete for external funding.
2. Supervise, train, mentor, and hire research staff, assess training and development needs, set goals and objectives for staff, conduct staff performance evaluation.
3. Work in multidisciplinary setting, with ability to work well independently and collaboratively. Develop scientifically meaningful collaborations to expand scope and depth of research program.
4. Participate in service to scientific community (grant review panels, membership in professional societies, peer review, education and outreach)
5. Communicate effectively in oral presentations, written manuscripts, and team meetings.
Mentor-Based Minority Postdoctoral Fellowship
Applicants must be U.S. citizens, not have more than 3 years of post-doctoral training, and hold a Ph.D or M.D. in a related field of research.
In addition, for the purposes of this award, underrepresented minorities are defined as those minorities who are underrepresented in the area of biomedical and behavioral research.
Those minority groups are:
A person having origins in any of the black racial groups of Africa.
Spanish, Hispanic or Latino:
A person of Mexican, Puerto Rican, Cuban, Central or South American, or other Spanish culture or origin, regardless of race.
American Indian and Alaskan Native:
A person having origins in any of the original peoples of North America, and who maintains a cultural identification through tribal affiliation or community recognition.
Native Hawaiian and Pacific Islander: A person having origins in any of the Pacific Islands, and who maintains a cultural identification through community recognition.
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Deadline: December 27, 2013