PLoS Clinical Trials

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Tony Rook
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PLoS Clinical Trials

Dear Colleague,

We are delighted to announce that PLoS Clinical Trials, the newest open-access journal from the Public Library of Science (PLoS), is now welcoming submissions in advance of its Spring 2006 launch. PLoS Clinical Trials will be freely accessible to all at

As a PLoS Medicine author or registrant, you will be familiar with the concept of open access that everyone can immediately access your work, and you retain copyright.

Call for Papers
We hope very much that you will support the goal of improving the reporting and availability of trial results, by submitting your work to PLoS Clinical Trials.

Benefits of publishing in PLoS Clinical Trials
Open access: you get the widest global audience for your work
Fast, rigorous peer review
Inclusivity: all randomized trials considered, irrespective of outcome
Rapid online publication
Listed in PubMed, articles cross-linked to trial registry records
All articles permanently archived in PubMed Central
Submissions are invited in particular in oncology, cardiovascular medicine, neurology, psychiatry and infectious diseases, but we welcome trials from all fields of healthcare. And remember, publication is not dependent on the results of your trial. Interim or follow-up analyses are welcomed.

Harold Varmus, Nobel Laureate and Co-founder of PLoS comments:

Members of the public participate in clinical trials, believing the results will increase knowledge. However, results are often hard to find or, worse still, are not reported at all, because journals tend to be interested in positive outcomes. PLoS Clinical Trials solves this, by providing a freely accessible online forum where all trials can be reported, irrespective of outcome.
To find out more about submitting a trial, go to

Content Alerts
The best way to stay current about new developments in PLoS Clinical Trials is to update your registration to include PLoS Clinical Trials content alerts, at Although PLoS Clinical Trials is multidisciplinary, information relevant to your specialty will be easily found through powerful, easy-to-use-linking and searching tools.

About PLoS
PLoS was founded by Harold Varmus, Patrick Brown, and Michael Eisen as a not-for-profit organization of scientists and physicians committed to making the worlds scientific and medical literature a public resource. PLoS Medicine (2004) followed PLoS Biology (2003; Impact Factor 13.9), and both, as well as subsequent community journals, have been received well by authors and readers.

Please contact us with your questions and feedback, which should be directed in the first instance to Emma Veitch, Publications Manager at eval(unescape('%64%6f%63%75%6d%65%6e%74%2e%77%72%69%74%65%28%27%3c%61%20%68%72%65%66%3d%22%6d%61%69%6c%74%6f%3a%65%76%65%69%74%63%68%40%70%6c%6f%73%2e%6f%72%67%22%3e%65%76%65%69%74%63%68%40%70%6c%6f%73%2e%6f%72%67%3c%2f%61%3e%27%29%3b')).


PLoS Clinical Trials Advisory Board
Mike Clarke
UK Cochrane Centre, Oxford, UK

Kay Dickersin
Johns Hopkins University, Baltimore, USA

Ben Djulbegovic
H. Lee Moffitt Cancer Center and Research Institute, University of South Florida, Tampa, USA

Christian Gluud
Copenhagen University Hospital, Copenhagen, Denmark

Pisake Lumbiganon
Khon Kaen University, Khon Kaen, Thailand

Musa Mayer
Author and breast cancer patient advocate, New York, USA

Adil Shamoo
University of Maryland, Baltimore, USA

Ida Sim
University of California, San Francisco, USA

Jimmy Volmink
University of Cape Town, Cape Town, South Africa


Emma Veitch
Publications Manager, PLoS Clinical Trials