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Making Antibodies That Neutralize HIV
Researchers have traced in detail how certain powerful HIV-neutralizing antibodies evolve, providing vital clues to guide the design of a preventiveHIV vaccine.
Learning How Support Cells Kill Nerve Cells in ALS
Supportive cells called astrocytes become toxic to muscle-controlling nerve cells in people who have amyotrophic lateral sclerosis. The finding offers new opportunities for investigating potential therapies.
Smoking and Bladder Cancer
Current cigarette smokers have a higher risk of bladder cancer than previously reported, according to new research. The study also found that the proportion of bladder cancer due to smoking in women is now the same as for men.
Immune regulation: (micro)Control of IFNγ
The microRNA miR-29 suppresses IFNγ production.
Regulatory T cells: Pursuing a germinal centre career
TReg cells expressing CXCR5 and BCL-6 regulate germinal centre responses.
MHC molecules: Cod's wallop? It's first class!
Atlantic cod have no MHC class II molecules but encode additional MHCclass I molecules and a unique TLR repertoire.
Structural variation in two human genomes mapped at single-nucleotide resolution by whole genome de novo assembly
Structural variation in two human genomes mapped at single-nucleotide resolution by whole genome de novo assemblyNature Biotechnology 29, 723 (2011). doi:10.1038/nbt.1904Authors: Yingrui Li, Hancheng Zheng, Ruibang Luo, Honglong Wu, Hongmei Zhu, Ruiqiang Li, Hongzhi Cao, Boxin Wu, Shujia Huang, Haojing Shao, Hanzhou Ma, Fan Zhang, Shuijian Feng, Wei Zhang, Hongli Du, Geng Tian, Jingxiang Li, Xiuqing Zhang, Songgang Li, Lars Bolund, Karsten Kristiansen, Adam J de Smith, Alexandra I F Blakemore, Lachlan J M Coin, Huanming Yang, Jian Wang & Jun Wang