RNAi - From Discovery to Therapies

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Tony Rook
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RNAi - From Discovery to Therapies


Keynote Presenters:

Jeremy Levin, Ph.D., Global Head,
Strategic Alliances,
Novartis Institutes for
BioMedical Research

Joseph Bolen, Ph.D., Senior
Vice President,
Research & Drug Discovery,
Millennium Pharmaceuticals


Cell-Type and Tissue-Specific RNAi
(Genes & Development Jan. 2006)
Miles Wilkinson, Ph.D., Professor,
Department of Biochemistry and Molecular Biology,
MD Anderson Cancer Center

siRNA Targeting TNF Modulates Host Resistance
to Herpes Simplex Virus (Nature Protocols in press)
Edouard Cantin, Ph.D., Professor and Associate
Chairman, Division of Virology, Beckman Research
Institute, City of Hope Medical Center

Genetic Analysis of Autoimmunity by
RNA Interference (Nature Genetics April 2006)

Patrick Stern Ph.D., Researcher,Center for
Cancer Research, Massachusetts
Institute of Technology

Reproducible and Inducible Knockdown
of Gene Expression in Mice (Genesis May 2006)
Jing Yu, Ph.D., Research Scientist,
Andrew McMahon Laboratory, Harvard University

Localized and Systemic In Vivo Delivery of RNAi
Devin Leake, Ph.D., Senior Scientist, Biology, Dharmacon

Target ID & Validation Toolbox Case Study #1:
Mark A. Labow, Ph.D., Executive Director,
Platform and Chemical Biology Department,
Genome and Proteome Sciences,
Novartis Institutes for BioMedical Research

Target ID & Validation Toolbox Case Study #2:
Michele Cleary, Ph.D., Research Fellow,
Rosetta Inpharmatics, LLC, a wholly owned
subsidiary of Merck and Co.

Know Your Resources: Cell Line
Characterization Prior to Target
Discovery and Validation with RNAi
Michael R. Cancilla, Ph.D., Associate Director,
Translational Medicine, Exelixis, Inc.

siRNA and the Problem of Getting What You Want
Finbarr Murphy, Ph.D., Managing Director,
Drug Discovery, EiRx Therapeutics Ltd

HT siRNA Screen for Genes that Regulate
Amyloidogenic Processing of -amyloid
Precursor Protein
Marc Ferrer, Ph.D., Senior Research Fellow,
Department of Automated Biotechnology,
Merck Research Laboratories

Phenotyping RNAi Libraries through Imaging
and Localization Studies
Bahram Parvin, Ph.D., Staff Scientist, Information &
Computing Sciences, Lawrence Berkeley National

RNAi Therapeutics: Advancements in Delivery
and In Vivo Efficacy (Nature May 2006)
Tracy Stage Zimmermann, Ph.D., Senior Scientist,
Alnylam Pharmaceuticals Inc.

Promoter RNAs Guide siRNA Mediated
Transcriptional Gene Silencing in Human Cells
Kevin Morris, Ph.D., Assistant Processor, Department
of Molecular and Experimental Medicine, The Scripps
Research Institute