PCR Error rates

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Big E
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PCR Error rates

Error Rates
1. Taq (Thermus aquaticus)
1.1 x 10-4 base substitutions/bp (Tindall and Kunkel, 1988)
2.4 x 10-5 frameshift mutations/bp (Tindall and Kunkel, 1988)
2.1 x 10-4 errors/bp (Keohavang and Thilly, 1989)
7.2 x 10-5 errors/bp (Ling et al., 1991)
8.9 x 10-5 errors/bp (Cariello et al., 1991)
2.0 x 10-5 errors/bp (Lundberg et al., 1991)
1.1 x 10-4 errors/bp (Barnes, 1992)

2. KlenTaq (Thermus aquaticus, N-terminal deletion mutant)
5.1 x 10-5 errors/bp (Barnes, 1992)

3. Vent (Thermococcus litoralis)
2.4 x 10-5 errors/bp (Cariello et al., 1991)
4.5 x 10-5 errors/bp (Ling et al., 1991)
5.7 x 10-5 errors/bp (Matilla et al., 1991)

4. Vent(exo-) (Thermococcus litoralis)
1.9 x 10-4 errors/bp (Matilla et al., 1991)

5. Deep Vent (Pyrococcus species GB-D)
No published literature. New England Biolabs claims fidelity
is equal to or greater than that of Vent.

6. Deep Vent(exo-)
No published literature.

7. Pfu (Pyrococcus furiosus)
1.6 x 10-6 errors/base (Lundberg et al., 1991)

8. Replinase (Thermus flavis)
1.03 x 10-4 errors/base (Matilla et al., 1991)

If anyone can add to this list please do so.