How do we gain human DM/PK/safety data quickly?

2 posts / 0 new
Last post
Xceleron
Xceleron's picture
How do we gain human DM/PK/safety data quickly?

 We use 14C microtracer studies to safely get data on human-specific PK and metabolism.  We can do this without full IND-enabling GMP and preclinical tox packages.  There are tremendous time/expense advantages by investigating a new drug entity quickly in humans
What are you doing?

Rina
Rina's picture
 

 
Hi Xceleron,
Can you please provide a protocol or a reference link for this method
Thank you