What are the solvents we can use instead of DMSO to dissolve a plant / fungi methanol extract?
You can use Isopropyl alcohol instead of DMSO. However, ths depends upon the downstream application.
I want to test cytotoxicity and genotoxicity of the extract (testing on blood cells)
Is isopropyl alcohol toxic to cells?
That will depend upon the final concentration of isopropanol. I recommend if your extract is soluble in ethanol than you can use it to about 20% concentration, prior to supplementing in cells.
DMSO can be used in same propotion as well.
thank you for the response.
final concentration of the solvent will be lower than 20%.I'll try it.