Maleimide

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ahmadhussain
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Maleimide

Please is any one know the reaction component for coupling Thiol-modified RNA with Maleimide

Hatuey
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The mercapto group in your

The mercapto group in your RNA will react with the maleimide via a nucleophillic addition reaction to the double bond inthe maleimide. You can find protocols inthe Molecular probes web site.