sample clean up

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Giggles
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sample clean up

Hi, i was just wondering if someone could help me with my sample clean up protocol for adipose tissue. I've done chloroform:methanol clean up to remove fats from sample but the 2D gels do not show any spots what so ever! its full of streaks! TCA pptn helped a bit more than that but it still does not give clear spots... does anyone know what else i can try? thanx!