How to quantitate the amount of drug bound to a protein inside the cell?

1 post / 0 new
Lopus
Lopus's picture
How to quantitate the amount of drug bound to a protein inside the cell?

Hi everyone,
                      I would like to know how to quantitate  amount of drug bound to its cellular target?
For example, if a drug  targets  microtubules in HeLa cells, how to quanitate the binding.

Please let me know,
Thank you,
Manu